Guthrie,S. E., Jones,L., Blackie,C. A., Korb,D. R. A Comparative Study Between an Oil-in-Water Emulsion and Nonlipid Eye Drops Used for Rewetting Contact Lenses. Eye and Contact Lens 2015;41,6:373-377. [ Show Abstract ]
OBJECTIVES: The purpose of this study was to determine the clinical impact of using SYSTANE BALANCE Lubricant Eye Drops (Alcon, Fort Worth, TX), an oil-in-water emulsion, as a rewetting eye drop in symptomatic contact lens wearers. METHODS: Subjects who had previously experienced contact lens discomfort (CLD), with a mean lens wearing history of 18.6Â±12.8 years, were randomly assigned to use a Test (SYSTANE BALANCE Lubricant Eye Drops; n=76) or control (habitual nonlipid contact lens rewetting eye drop; n=30) drop over their contact lenses within 5 min of lens insertion and then subsequently at 2 hr intervals up to a maximum of 4 drops per eye daily for a 1-month period. Assessments of subjective comfort, comfortable wearing time, lid wiper epitheliopathy (LWE), and corneal staining were conducted at baseline and after 1 month, after 6 hr of lens wear. RESULTS: Comfort, wearing time, LWE, and corneal staining all showed statistically significant improvements in the test group using SYSTANE BALANCE Lubricant Eye Drops at the 1-month visit compared with baseline data (all P<0.01) and compared with the control group at the 1-month visit (P<0.01, P=0.01, P<0.01, and P=0.03, respectively). CONCLUSIONS: The use of SYSTANE BALANCE Lubricant Eye Drops as a rewetting drop in a group of wearers who experienced symptoms of CLD improved subjective comfort scores, increased comfortable wearing time, and reduced signs of LWE and corneal staining, when compared with the use of nonâ€“lipid-containing contact lens rewetting eye drops. Â© 2015 Contact Lens Association of Ophthalmologists, Inc.
Woods,J., Guthrie,S. E., Keir,N., Dillehay,S., Tyson,M., Griffin,R., Choh,V., Fonn,D., Jones,L., Irving,E. Inhibition of defocus-induced myopia in chickens. Investigative Ophthalmology and Visual Science 2013;54,4:2662-2668. [ Show Abstract ]
PURPOSE. To determine the effect of wearing a lens with a unique peripheral optical design on the development and progression of defocus-induced myopia in newly hatched chickens.METHODS. Eighty-five newly hatched chickens underwent bilateral retinoscopy and A-scan ultrasound to determine their refractive error and axial length. They were randomly divided into Control and two Test groups, in which each chicken was fitted with a goggle-lens over the right eye, with the left eye remaining untreated. The Control group wore a lens of power - 10.00 diopters (D) of standard spherical optical design. The two Test lenses both had a central optical power -10.00 D, but used different peripheral myopia progression control (MPC) designs. For all groups, retinoscopy was repeated on days 3, 7, 10, and 14; ultrasound was repeated on day 14.RESULTS. On day 0 there was no statistical difference in refractive error (mean +6.92 D) or axial length (mean 8.06 mm) between Test and Control groups or treated and untreated eyes (all P > 0.05). At day 14, 37 (43.5%) of 85 chickens had not experienced goggle detachment and were included in the final analyses. In this cohort there was a significant refractive difference between the treated eyes of the Control group (n = 17) and those of Test 1 (n = 14) and Test 2 (n = 6) groups (both P < 0.01): Control -4.65 ± 2.11 D, Test 1 +4.57 ± 3.11 D, Test 2 +1.08 ± 1.24 D (mean ± SEM). There was also a significant axial length difference (both P < 0.01): Control 10.55 ± 0.36 mm, Test 1 9.99 ± 0.14 mm, Test 2 10.17 ± 0.18 mm.CONCLUSIONS. Use of these unique MPC lens designs over 14 days caused a significant reduction in the development of defocus-induced myopia in chickens; the degree of reduction appeared to be design specific. © 2013 The Association for Research in Vision and Ophthalmology, Inc.
Stahl U, Keir N, Guthrie S, Jones L. Effect of monocular lens wear on ocular comfort. TFOS conference, Montpelier, France, 2016.
Jones L, Guthrie S, Dumbleton K. Is there a relationship between care system and compliance?. Asian Cornea and Contact lens Conference, Hong Kong, 2016. [ PDF ]
Guthrie S, Dumbleton K, Jones L. Is there a relationship between care system and compliance?. BCLA Clinical Conference and Exhibition, 2015. [ PDF ]
Guthrie S, Woods J, Dumbleton K, Fonn D, Jones L. Contact lens discomfort management strategies of ECPs. Optom Vis Sci 2015;92: E-abstract 155050. [ PDF ]
Dillehay S, Woods J, Situ P, Guthrie S, Paynor R, Griffin R, Tyson M, Jones L. Comparison of Three Power Levels of A Novel Soft Contact Lens Optical Design to Reduce Suspected Risk Factors for the Progression of Juvenile Onset Myopia. Invest Ophthalmol Vis Sci 2014;55: E-abstract 3637.
Guthrie S, Woods J, Keir N, Dillehay S, Tyson M, Griffin R, Fonn D, Jones L, Irving E. Controlling lens induced myopia in chickens with peripheral lens design. Optom Vis Sci 2011;88:E-Abstract 110421.
Woods J, Guthrie S, Keir N, Choh V, Fonn D, Jones L, Irving E. Myopia development – what can the chicken tell us?. Contact Lens & Anterior Eye 2011;34,Supplement 1:s13.
Woods J, Guthrie S, Keir N, Dillehay S, Tyson M, Griffin R, Jones L, Irving E. The effect of a unique lens designed for myopia progression control (MPC) on the level of induced myopia in chicks. Invest Ophthalmol Vis Sci 2011;51:E-Abstract 6651.
Dumbleton K, Woods C, Jones L, Guthrie S, Fonn D. Patient and practitioner compliance with silicone hydrogel and daily disposable lens replacement. Contact Lens & Anterior Eye 2009;32,5:213.
Jones L, Brodland G, Horst C, McDonald M, Guthrie S. A novel method for measuring contact lens tensile properties. Contact Lens & Anterior Eye 2009;32,5:254.
Dumbleton K, Richter D, Guthrie S, Woods C, Jones L, Fonn D. Patient and practitioner compliance with silicone hydrogel and daily disposable lens replacement. CAO (Charlottetown, PEI), 2009.
Brodland G, Jones L, Horst C, McDonald M, Guthrie S. A novel method for measuring contact lens tensile properties. Optom Vis Sci 2009;86:E-abstract 095818.
Dalton K, Jones L, Guthrie S. pH, Osmolality and viscosity of artificial tears. Optom Vis Sci 2008;85: E-abstract 85310.
Dalton K, Jones L, Guthrie S. Physical properties of artificial tears. Contact Lens & Anterior Eye 2008;31,5:272.
Guthrie S, Simpson T, Varikooty J, Fonn D. Background subtraction and contrast enhancement for interferometric images of the human corneal tear film. Invest Ophthalmol Vis Sci 2006;47:E-abstract 2399.
Guthrie S, Dumbleton K, Jones L. Is There a Relationship Between Care System and Compliance?. Contact Lens Spectrum 2016;31,April:40-43.
Guthrie S, Dumbleton K, Jones L. Financial Implications of Patient Compliance. Contact Lens Spectrum 2014;29,December:42-45.
Guthrie S. Effect of dual-focus soft contact lens wear on axial myopia progression in children - An article review. ContactLensUpdate.com 2011.
Richter D, Dumbleton K, Guthrie S, Woods C, Jones L, Fonn D. Patient and practitioner compliance with silicone hydrogel and daily disposable lens replacement in Canada. Canadian Journal of Optometry 2010;72,1:10-19.
Jones L, Sorbara L, Stahl U, Thom M, Guthrie S. Contact Lens Compendium: Contact Lenses and Solutions Available in Canada. Vol 43. 2017.
Jones L, Sorbara L, Stahl U, Thom M, Guthrie S. Contact Lens Compendium: Contact Lenses and Solutions Available in Canada. Vol 42. 2016.
Jones L, Sorbara L, Stahl U, Thom M, Guthrie S. Contact Lens Compendium: Contact Lenses and Solutions Available in Canada. Vol 41. 2015.
Jones L, Sorbara L, Stahl U, Thom M, Guthrie S. Contact Lens Compendium: Contact Lenses and Solutions Available in Canada. Vol 40. 2014.
Jones L, Sorbara L, Stahl U, Guthrie S, Menzies K, Rossy J, Thom M. Contact Lens Compendium: Contact Lenses and Solutions Available in Canada. Vol 39. 2013.